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When the intestinal barrier is compromised, increased antigen exposure activates these mast cells, creating a systemic inflammatory state that amplifies allergic reactivity everywhere

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial

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Trivedi, A

Nature 2021;594, 100-105, doi:10.1038/s41586-021-03547-7

[DOI] [PubMed] [Google Scholar] Deng W, Aimone JB, Gage FH
