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In another study, (13) murine models with experimentally induced impairment in neurological functioning were exposed to Humanin and a similarly structured peptide, PAGA, to determine the potential of both peptides on the brain function of the murine models

5 Impact and mechanism of local anesthetics on mitochondria Local anesthetics such as lidocaine, bupivacaine, and ropivacaine block sodium ion channels on nerve fibers, inhibiting pain signal transmission, reduce general anesthesia requirements during surgery, and assist in postoperative pain management

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Zhou Y, Teng X, Han M, Shi J, Li C, Zhang X, et al

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Choi, A.L., Weihe, P., Budtz-Jrgensen, E., Jrgensen, P.J., Salonen, J.T., Tuomainen, T.-P., Murata, K., Nielsen, H.P., Petersen, M.S., Askham, J., and Grandjean, P., 2009, Methylmercury Exposure and Adverse Cardiovascular Effects in Faroese Whaling Men: Environmental Health Perspectives , v