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Tocopherols reduce lipid radicals within the membrane, and the resulting tocopherol radicals are then directly re-reduced by ascorbate 41

Polymer-based nanoparticles offer a versatile platform for intranasal brain delivery due to their tunable degradation, controlled drug release profiles, and potential for functionalization

AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1

Future clinical studies are needed to assess functional vascular plaque, size, stabilization, cardiovascular event rate, and cardiovascular-related hospitalization and mortality rates for cardiovascular endpoints

Placebo showed essentially no change at 0.3%

Lancet 2023