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Diosgenin Protects against Podocyte Injury in Early Phase of Diabetic Nephropathy through Regulating Sirt6

The open-label trial (NCT05606614) will be evaluating the safety, tolerability, and preliminary efficacy of a low dose (5E14 vector genomes per kilogram, vg/kg) and a high dose (1E15 vg/kg) of TSHA-102 in up to 18 women, 18 or older, with Rett syndrome caused by a MECP2 gene mutation

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Haug, Ralf Schiebel, Daniel M

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