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Early detection of pathogen-associated molecular patterns (PAMP) expressed by the virus is sensed and mediated by pattern recognition receptors (PRRs), such as the Toll-like receptor (TLR)-family or RIG-I like receptor

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Orthop Res

However, similar to what we observed for strep-MBP-GRXC2, strep-MBP-HsGRX1 became oxidized already upon addition of GSH, resulting in two main protein species which persisted over a wide range of GSH/GSSG ratios (Fig

The pellet was solubilized in 15 l of ultrapure water treated with DEPC and incubated for 15 min with 1 U of DNAse I, and the enzyme was inactivated by heating at 65C for 10 min