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C (Comparison): intramuscular administration of Vitamin B12

Vitamin B12 is an essential nutrient that functions as a coenzyme in metabolic processes, remethylation of homocysteine to methionine, and converts methyl malonyl-CoA to succinyl-CoA

Clinical studies specifically monitoring glucose metabolism through oral glucose tolerance tests found no significant changes in glucose handling, and fasting insulin levels remained stable throughout treatment periods lasting up to 24 weeks