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181,403 Upon ER stress, unfolded proteins accumulate in the ER, leading to gradual dissociation of BiP from IRE1, PERK, and ATF6, which activates them

Trigger points are small, sensitive spots in muscles that can cause pain and stiffness

Both acute and chronic stress may be detrimental to health

The structure of the complex containing ascorbate or GSH was solved by the ligand soaking method
This means faster symptom relief (see Benefits below)
