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Therapeutic Targeting of the Proinflammatory IL-6-JAK/STAT Signalling Pathways Responsible for Vascular Restenosis in Type 2 Diabetes Mellitus

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6.2.3.2 Myelin vacuolization and demyelination NO-induced Vit B12 inactivation results in MMA accumulation ( 6.2.3.3 Cytokine dysregulation and myelin swelling Elevated levels of proinflammatory cytokines, such as TNF-, and reduced levels of epidermal growth factor have been observed in Vit B12-deficient states ( 6.3 Clinical manifestations of nervous system injury NO-induced injuries are classified into acute, subacute, and chronic phases