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Reapply every two hours, or more often if you are sweating or swimming
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Recombinant pathogenic protein-based serological assays may attain excellent sensitivity and specificity because of the high concentration of immunoreactive antigens and the lack of nonspecific moieties present in whole-cell preparations from the blood of experimentally infected animals
The practical implication: refrigerate, use within the labeled shelf life, and avoid exposing the vial to repeated temperature fluctuation

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The 38 week window when even minor molecular disruptions can alter fetal architecture permanently
