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Approximately 50-70% of adult and pediatric SLE patients have an upregulated IFN signature, a cluster of IFN-stimulated genes, that correlates with disease activity and severity (122)

Ferran Barrachina, Program in Membrane Biology, Nephrology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States This article was submitted to Reproduction, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

It may also help manage symptoms related to autoimmune disorders by reducing chronic inflammation and oxidative stress

Methods The study was an open label, single arm, multicenter, pilot trial

[DOI] [PMC free article] [PubMed] 47.Pizarro-Galleguillos BM, Kunert L, Brggemann N, Prasuhn J

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