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Paradoxically, this same mechanism may underlie its potential pro-cancer effects: by boosting GSH production, cancer cells can better protect themselves from oxidative damage caused by ROS (Ramachandran and Jaeschke, 2021)

Genetic depletion of Slc7a11 or Gpx4 in mouse embryonic fibroblasts leads to ferroptosis [40, 41]

10.1089/jwh.2013.4334 [DOI] [PMC free article] [PubMed] [Google Scholar] Sukonthanonta A

Endogenous fluorescence carbon dots derived from food items

In: Holland-Frei Cancer Medicine, 2017

Moreover, the observation that adding GLP-1MK-801 treatment on top of semaglutide leads to an additional weight loss of 7% in mice that have reached a weight loss plateau with semaglutide provides additional support for integrating NMDA receptor antagonism in next-generation weight loss therapeutics