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Moll J, Florian K, Franco W, Alexander G, Thomas DB, Martin H, et al

Jin et al., 2017) show that sodium selenate reduces Tau phosphorylation in vivo and in vitro by activating serine/threonine-specific protein phosphatase 2A (PP2A), rescuing cognitive deficits in Tau transgenic mice (e.g., P301L, K369I, and Tau441 models)

The peptide demonstrates remarkable stability in human gastric juice, remaining intact for more than 24 hours, which allows for effective oral administration in addition to systemic delivery routes

M., Cheng K., et al., The Importance of Apparent pKa in the Development of Nanoparticles Encapsulating siRNA and mRNA, Trends in Pharmacological Sciences 42, no
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia

10.1073/pnas.2104666118 CrossRef Google Scholar View reference in article 43 PietrangeloA
