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8.6.5 Other assays Relevant data are summarized in Table 7

In addition, purinoreceptor subtype 7 activation has been observed to cause caspase-1 activation, which is ultimately involved in the expression of cyclooxygenase 2 and prostaglandin E2 and IL- production

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Additionally, TSA was found to downregulate microRNA-33 expression in THP-1 macrophages, thereby reducing oxidized low-density lipoprotein (ox-LDL)-induced expression of pro-inflammatory cytokines IL-1, IL-6 and TNF- (42)

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