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doi: 10.3390/antiox11101935

Targeting NOX enzymes, especially NOX4, has shown promise in experimental models, and the dual NOX1/NOX4 inhibitor GKT137831 (setanaxib) has demonstrated anti-fibrotic efficacy in Phase II trials

We found that AMPH can cause endocytosis of NET as well as EAAT3 in NE neurons

Consequently, tumors in miR-143/145-deficient animals exhibit reduced angiogenesis, increased apoptosis, and restricted expansion due to limitations in their ability to engulf pulmonary vasculature [90]

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doi: 10.1016/j.jad.2011.06.005
