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Description

Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalization

A., Guilleminault, C

Thus, in rats with occluded blood vessels, at 1 and 24 h, BPC 157 demonstrated a particular specificity within the pathways (at least, Egr, Nos, Srf, Vegfr, Akt1, Plc , and Kras ) and vessels involved (Vukojevic et al., 2018)

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Although mutations of residues 294299 also resulted in decreased activity, a different substrate preference was noticed in variants, such as G296F, which displayed higher activity toward DOPA than tyrosine compared with WT