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Additionally, stroke-associated microglia feature increased autophagy in associated with an enhanced inflammatory response (319321)

During cellular stress, the expression of several proto-oncogene tyrosine-protein kinase SRC and Serine/threonine-protein kinase B-raf such as SRC, RAS, BRAF, and MEK takes place and activates the expression of extracellular-signal-regulated kinase ERKs (ERK1/ERK2)

Purinergic Signal 15 , 465476 (2019)

Another way is by altering lipid metabolism, converting dietary components such as choline, lecithin, and carnitine into TMAO which can increase the uptake of lipids by cells in the blood vessel walls and promote the formation of plaques (122)