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Therefore, with the deepening of research, the regulatory pathways of ferroptosis in the antioxidant system are not limited to GSH-dependent antioxidant pathways, but also can play a role in regulating ferroptosis through GSH-independent antioxidant pathways, which means that there may be more regulatory mechanisms related to ferroptosis waiting for us to further explore

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However, insulin sensitivity and glucose tolerance were maintained, likely owing to an increased conversion of saturated fatty acids (known to cause insulin resistance) to monounsaturated fatty acids mediated by stearoyl-CoA desaturase-1 (SCD1) [52]

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