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Dehydroabietic acid promotes the expression of GSH and GPX4, reduces ROS accumulation, reduces hepatic lipid peroxidation, inhibits hepatic ferroptosis, and improves NAFLD ( 6.2.2 Pathway-specific regulation of ferroptosis and lipid accumulation Diosgenin significantly alleviates ferroptosis and ROS accumulation in HepG2 cells by regulating the ACSL4/LPCAT3/ALOX15 pathway, thereby mitigating NAFLD (Wang et al., 2025a)

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Furthermore, all doctors agreed to follow the criteria identified in our future use of vitamin B12

Common causes of exogenous pigmentation are henna, colored nail lacquer, nicotine, dirt, and potassium permanganate.[1] Reversible melanonychia has been reported with vitamin-B12 deficiency, especially in dark-skinned individuals.[2] Reduced glutathione levels in B12 deficiency causes disinhibition of tyrosinase, the major enzyme involved in melanogenesis.[3] Strict vegetarian diet, knuckle pigmentation, low serum vitamin-B12 levels, and a raised serum homocysteine along with raised methylmalonic acid levels (c.f

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