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Mitochondrial dysfunction further enhances protein misfolding and oxidative stress

though the first use of the ligand for a brain-targeting prodrug of methotrexate was reported in 1991 [22]

[DOI] [PubMed] [Google Scholar] 135.Lu SC, Huang ZZ, Yang J, Tsukamoto H

Freeman and Company, New York, p 732 [Google Scholar] Sujayev A, Garibov E, Taslimi P, Gulcin I, Gojayeva S, Farzaliyev V, Alwasel SH, Supuran CT (2016) Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase
