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Contribution of Lys256 and Lys413 to the mIDH2 reaction To determine the K m and k cat values of isocitrate and NADP + for the two most affected mutants, K256Q and K413Q, we conducted a steady-state kinetics analysis
Cartilage and bone damage in rheumatoid arthritis
Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease
(Boraginaceae)] which is commonly used as an antiinflammatory or detoxicant agent, showed significantly reduced serum concentrations of ALT, AST, ALP, and inflammatory markers (Teng et al., 2012)
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Like the IRE1/XBP1s axis, PERK/ATF4 signaling is also implicated in mediating the apoptotic response to persistent and excessive ER stress
