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Using this approach, we discovered a novel role for the melanogenesis-associated transcription factor, or MITF, in repressing the expression of innate immune genes within cells of the melanocyte lineage in mice. The importance of this repression is revealed in animals that have a predisposition for hair-graying

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As a synthetic analog, DSIP exhibits poor oral bioavailability and is typically administered via parenteral routes for research purposes

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