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Constipation during B12 supplementation is often due to other ingredients such as iron or calcium in multivitamin formulations

J Clin Invest 106 : 483491

The KLF1 transcription factor represses -globin expression by activating BCL11A, with haploinsufficiency causing high HbF levels [17], [34], [35]

Researchers are encouraged to identify whether the subclinical deficiency or deficiency itself of this vitamin is a risk factor for COVID-19 complications, and it is necessary to carry out intervention studies with vitamin B 12 supplementation in both the adjuvant treatment of mild, moderate, and severe COVID-19 and postCOVID-19, with a focus on minimizing symptoms related to the musclegutbrain axis

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