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Downregulation of blood-brain barrier phenotype by proinflammatory cytokines involves NADPH oxidase-dependent ROS generation: ramifications for interendothelial adherens and tight junctions

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Science 312 , 233236 (2006)

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[5], [6], [7] Transcription factors of the FOXO family specifically FOXO1, FOXO3, FOXO4, and FOXO6 are key mediators of insulin and IGF signaling, participating in the regulation of a wide range of cellular processes, including metabolism, cell growth and differentiation, response to oxidative stress, autophagy, senescence, and aging-related processes

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& Skog, O

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