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In the synthesizing process, GABA is produced from glutamate by the glutamic acid decarboxylase (GAD) enzyme that requires pyridoxal-5-phosphate (PLP) as a cofactor 24

Front Pharmacol 9:336 Chaurasiya ND, Ibrahim MA, Muhammad I, Walker LA, Tekwani BL (2014) Monoamine oxidase inhibitory constituents of propolis: kinetics and mechanism of inhibition of recombinant human MAO-A and MAO-B