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Collectively, the scientific data on mitragynine and 7-hydroxymitragynine suggest that kratom tea might indeed be an effective alternative to opioids against pain

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Given recent findings that M1/M2 phenotypes are not mutually exclusive in macrophages 26 , the cells in the treatment groups may undergo a state shift

Proc Natl Acad Sci U S A (1988) 85(13):488993.10.1073/pnas.85.13.4889 165 LaronZKlingerBJensenLTErsterB

Skin and Other Effects: Very rarely, severe skin rashes or abdominal pain have been reported
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