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The ATPase stimulation serves as a confirmation of the interaction between imidazole ketone erastin and piperazine erastin and P-gp, given the close connection between ATP hydrolysis and substrate efflux [22]
2017;4:ofw281
In: Fink G (ed) Encyclopaedia of stress
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GSH, a ubiquitous sulfhydryl-containing tripeptide produced by most mammalian cells, is usually present as a reduced form, but GSH is converted into its oxidized form (GSSG) by stimulation such as oxidative stress
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