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Gene editing (CRISPR-Cas9) trials As of 2025, no phase 3 clinical trials have been completed for CRISPR-Cas9based therapy in T1D

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Metal-based nanozymes Copper CuxO nanoparticle clusters containing phenylalanine have been shown to carry out multiple superoxide dismutase, catalase, glutathione peroxidase, and peroxidase-mimicking enzymes (Hao et al

Many peptides referenced are investigational and not FDA-approved for all uses

Physical therapy addresses movement patterns, strengthens supporting structures, and guides progressive loading during recovery