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The computations were partly performed using the supercomputers at the RCCS, The National Institute of Natural Science, ISSP and The University of Tokyo

GSH is also responsible for the detoxification of acrolein, a toxic byproduct of polyamines in the brain [57]

Injectable Nanostructured Colloidal Gels Resembling Native Nucleus Pulposus as Carriers of Mesenchymal Stem Cells for the Repair of Degenerated Intervertebral Discs

It has also been demonstrated that the treatment of cells with thiols like -mercaptoethylamine (MEA), S -2-aminoethylisothiourea (AET) and cysteine cause an increase in the free GSH content in the cell by triggering a release of the nucleo-protein bound GSH [45]

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As our multi-stage subtypes provide a refinement of melanoma differentiation, we built a predictive model trained on our cell line expression profiles to predict differentiation subtypes of cell lines profiled in publicly available pharmacogenomics resources (Figure 3A)