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FINANCIAL SUPPORT This research was funded by the Directorate of Higher Education of the Ministry of Education, Culture, Research, and Technology of the Republic of Indonesia with the IPB Higher Education Research Grant scheme 2021 (contract No

Benjamin TanJohnson was involved in, formal analysis, investigation, and writingreview and editing

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NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is the mammalian homolog of the mitochondrial enzyme encoded by the yeast MIS1 gene