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All the evaluations for assessment were administered in the form of scales or questionnaires completed by the patients without any interference by the clinicians, at baseline and during the subsequent visits, as routine evaluations

L-Carnitine 1500 Extreme MEGA CAPS -

Free carnitine directly facilitates mitochondrial fatty acid uptake and -oxidation [31], Acylcarnitines are esters formed by conjugation of free carnitine with fatty acyl groups of varying chain length, and are categorized as short-chain ( C6, e.g., acetylcarnitine C2, propionylcarnitine C3), medium-chain (C7-C12, e.g., octanoylcarnitine C8, decanoylcarnitine C10), and long-chain ( C13, e.g., palmitoylcarnitine C16, stearoylcarnitine C18) derivatives [32,33,34]

Four months after cessation of LC supplementation, plasma TMAO reached a pre-supplementation concentration, which was stable for the following 8 months [60]

However, the effectiveness of L-Lysine in this regard is still a subject of research and debate

Units: blood lactate, percent change from baseline