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have shown that efficient binding of methemoglobin to band 3 protein, requires a preceding peroxidation of the cytoplasmic portion of band 3 protein (Arashiki et al., Anti-band 3 NAbs and induced anti-lactoferrin antibodies Anti-band 3 NAbs, as isolated from plasma of healthy blood donors with blood group O or from Sandoglobulin bound to band 3 and exclusively to the 68/55 kDa chymotryptic fragment of band 3, but not to the carbohydrate-containing, 38/35 kDa fragment (Lutz et al., 1984)

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J Med Chem 66(17):1163211655

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4.4.2.2 Anti-immune cell surface antibodies B cell depletion therapy employing anti-CD20 antibodies presents a novel strategy for modulating adaptive immunity in DKD

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