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However, our bodies' glutathione levels can be compromised due to factors such as aging, poor diet, environmental stressors, and chronic illnesses

Activated microglia accumulate near neurons and are the main contributors to neuroinflammation in AD [146,147,148,149,150,151]

Determination of lipid peroxidation and protein carbonylation We used a lipid peroxidation assay kit (Abcam) to detect malondialdehyde (MDA) in samples

Ketosis involves increased oxidation of fatty acids and the resulting ketone bodies (-hydroxybutyrate, acetoacetate and acetone) are used as the main energy substrate [37]

S-5-HT assay The S-5-HT (as well as all other laboratory) samples were collected at the Helsinki University Hospital Laboratory, where the S-5-HT protocol includes dietary restrictions for two days prior to the sample and collecting the samples between 8 10 am