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The tumor microenvironment represses T cell mitochondrial biogenesis to drive intratumoral T cell metabolic insufficiency and dysfunction
This further illustrates the beneficial long-term effects of lactate and lactylation on enhancing brain neuroplasticity and slowing neurodegeneration [79]

Valproic acid alleviates memory deficits and attenuates amyloid- deposition in transgenic mouse model of Alzheimers disease

The trace element selenium (Se) exerts its essential role as the 21st amino acid, selenocysteine (Sec) [25]

(2019)10(10):e00078
doi: 10.1016/j.biopha.2020.110695