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PINK1 insufficiency functions as an early regulator of neuronal innate immunity, since PINK1 /Parkin might lower inflammatory circumstances that initiate immune response-eliciting pathways by cutting mitochondrial antigen presentation in the mouse model of PD [379,380]

PMC 3687347

Bpc-157, being smaller at 15 amino acids, tends to concentrate more heavily at injection sites while still providing some systemic benefits

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The most prevalent gene-associated PD risk factor is the catabolism of the glycolipid glucocerebroside into glucose and ceramide in the lysosome [227,228], which causes Gaucher disease

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