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Overarching Principle The fundamental principle of regulation of medicines is to optimise timely access to effective treatments while reducing the risk of harm from improper use

Later, in response to yet unidentified triggers, silent autoimmunity eventually turns into a clinically apparent inflammatory disease such as RA

Over-the-counter oral antihistamines can help with itching, and a cool compress reduces heat and swelling

Moreover, principal component analysis (PCA) of gene expression data from shoots and roots (Supplementary Fig