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All studies are described in Table 4

Second, we did not place restrictions on concomitant medications during the course of the study

The ARIC investigators

These findings are similar to data recently published by us in clinical cohorts, with E4 carriers exhibiting relatively higher SCAs and lower LCAs with AD even at the pre-clinical stages compared to controls and other APOE genotypes (Huguenard et al., 2022)

"Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for the prevention of taxane-induced neuropathy in women undergoing adjuvant breast cancer therapy." J Clin Oncol 31(20): 2627-2633

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