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This idea is consistent with our data of dimerization of aMD5 that requires a long linker, to induce agonistic activity ( vide infra )

doi: 10.1021/acs.biochem.7b00859 93 AbdElrazekDAIbrahimMAHassanNHHassanenEIFarrohKYAbassHI

Safety Concerns Therapeutic peptides are generally considered safe with low immunogenicity and a favorable adverse effect profile compared with many pharmacologic agents

The FDA has also flagged safety concerns regarding certain bulk substances used in compounding, as well as broader compounding risks

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