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Such dual modulation resembles the anti-inflammatory effects reported for GLP-1 receptor agonists, which inhibit NF-B activation and macrophage infiltration [41]

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Celastrol enhances leptin sensitivity, an essential hormone for regulating appetite and metabolism [32]

10.5187/jast.2021.e21 [DOI] [PMC free article] [PubMed] [Google Scholar] Johnson S

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