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Cancer Cell 37 , 767785 (2020)

Molecular Chaperones in Protein Folding and Proteostasis

Emine Cosar, MD

This Cop1 is responsible for driving TAM recruitment, M2 polarization, and promoting resistance to immunotherapy and its inhibition leads to enhanced antitumor responses to PD-1 blockade (156)

Rotate sites weekly to prevent lipohypertrophy (fatty thickening) and avoid injecting into scars, moles, or irritated skin
