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10.1155/2017/3940241 159 RobinsonR.SrinivasanM.ShanmugamA.WardA.GanapathyV.BloomJ.et al (2020)

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Simultaneously, released Cu 2+ causes redox reaction with the intracellular overexpressed GSH, and subsequently produces Cu + for initiation of Fenton-like reactions, resulting in the production of OH and robust anticancer therapy

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Absence of the NOD2 protein renders epithelia more susceptible to barrier dysfunction due to mitochondrial dysfunction

Furthermore, they help maintain the elasticity of connective tissues