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2.2 Animal experiments and sample collection Adult male Sprague-Dawley rats weighing 200 20 g were acquired from the Animal Breeding Center at the Heilongjiang University of Traditional Chinese Medicine (Heilongjiang, China) [License No

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Released cellular components from dying adipocytes, including mitochondrial DNA fragments and oxidized lipids, trigger hepatic Kupffer cell activation via TLR9 signaling, promoting liver inflammation and fibrosis (393)

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