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It functions as a potent vasodilator, modulates smooth muscle activity in the gastrointestinal tract, and participates in neurotransmission in the central and peripheral nervous systems (Lelievre et al., 2008)

The brain regions where BDNF exerts its strongest influence are the hippocampus, the prefrontal cortex, and the basal forebrain

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J Immunother Cancer 4:111 Kind F, Michalski K, Yousefzadeh-Nowshahr E, Meyer PT, Mix M, Ruf J (2022) Bone marrow impairment during early [177Lu] PSMA-617 radioligand therapy: haematotoxicity or tumour progression