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The pivotal primate study was published in Science Translational Medicine in 2011
[PMC free article] [PubMed] [Google Scholar] 401

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The development and pattern of myelination follows a well-described neuroanatomical arc [15], progressing in a posterior-to-anterior and centre-outwards spatiotemporal pattern that corresponding to maturing cognitive functions [16]

Emergency Protocols : Established procedures for managing serious adverse reactions, including immediate access to medical care