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We additionally analyzed the frequencies of commonly occurring obesity-related metabolic comorbidities (e.g

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J Appl Physiol

Injection site reactions including erythema, pruritus, or mild indurationoccur in some patients, with frequency varying by product (from low single-digit percentages to over 10%)

Potential mechanisms include promoting access of soluble lipases to hydrophobic substrates, facilitating the formation of complexes between lipases and lipolysis-associated proteins, and stabilizing lipases at the surface of the lipid droplet