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The abnormal release of Ca 2+ from the mitochondria to the cytosol leads to the activation of microglia, neuroinflammation, and finally, cell death [29, 93]

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DPP-4 inhibitor impedes lipopolysaccharide-induced osteoclast formation and bone resorption in vivo

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Furthermore, because ALCAR can influence thyroid hormone activity by blocking the entry of thyroid hormone into the cell nucleus, individuals with hypothyroidism or those taking thyroid replacement medications should use ALCAR with caution and under medical supervision

Global health: a one health approach