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Conclusion NAC exerts a protective effect against mercury-induced cytotoxicity and genotoxicity in rat lungs by scavenging mercury and modulating the expression of oxidative stress-related genes

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[5] The pathophysiology of anaphylaxis and anaphylactoid reactions stems from the effect of histamine on vascular and bronchial smooth muscle leading to cutaneous vasodilation and third-spacing (hives, rash, pruritis), bronchospasm (wheezing), and reduced systemic vascular resistance (tachycardia, hypotension)

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JACC Heart Fail