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Mechanistically, CAT promotes ubiquitination and proteasomal degradation of HIF-1, thereby attenuating osteoclast differentiation and bone resorption (Figure 4)

NAC also acts as a transcription factor activating the RAS-ERK pathway, rescuing neurons from apoptotic cell death [52]

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Nanocarriers including PLGA-based nanoparticles emerge as a promising solution, offering enhanced drug stability, controlled-release, and targeted delivery

Each person has a different balance between ACE and ACE2 and can be more prone to inflammation if ACE prevails
