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430 These findings suggest that iron metabolism is abnormal in the cells of Friedreichs Ataxia models, and regulation of iron metabolism may have some ameliorative effects on Friedreichs Ataxia

doi: 10.1016/j.biortech.2021.126157

Mori Y, Katsumata K, Tsuchida A, Aoki T

When the neurons in the substantia nigra are damaged in large numbers, the loss of dopamine prevents normal function in basal ganglia and causes the motor symptoms of PD: tremor, rigidity, impaired balance, and loss of spontaneous movement [56]

Emerging targets for cardioprotection All the above-described overlooked players and cell death mechanisms represent targets for cardioprotection