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Energy shortage conditions, such as glucose limitation and oxygen deprivation, trigger AMPK activation

Supercaps 9 , e202500488 (2025)

Strikingly, PA14 infection also robustly increased gut granule fluorescence (Fig

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Moreover, we validated the relationship between GSH-regulated replication stress and JMF4073 sensitivity in a number of TKI-insensitive human CML blast-crisis cells, and present the evidence of the synthetic lethality by targeting glutathione biosynthesis with JMF4073 in these cells