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Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans

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doi: 10.1111/eci.2011.41.issue-4 60 KanY-YChangY-SLiaoW-CChaoT-NHsiehY-L

Favrod-Coune and B

Until then, it would be reasonable for physicians prescribing metformin singly or in combination with these drugs to monitor the patients vitamin B 12 status and to prescribe vitamin B 12 supplements if blood biomarkers or clinical symptoms are consistent with a low vitamin B 12 status